given the high-dimensionality ( thousands of genes ) and small sample sizes ( often < 30 ) encountered in these datasets, an honest assessment of sampling variability is crucial and can prevent the over-interpretation of spurious results dna芯片数据具有高维(成千上万个基因)和样本小(通常小于30)的特点,为了避免对伪结果进行分析,准确估计抽样方差很重要。